Gene Combo May Signal Prostate Cancer ; Finding Could Lead to Predictive Blood Test

Summary


Scientists have taken a key step toward revealing the causes of prostate cancer, finding that a combination of five gene variants dramatically raises the risk of the disease. Added to family history, they accounted for nearly half of all cases in a new study.

The discovery is remarkable not just for the big portion of cases it might explain, but also because this relatively new approach looking at combos rather than single genes may help solve the mystery of many complex diseases like cancer and diabetes that are thought to involve multiple genes or interactions between them.

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Gene Combo May Signal Prostate Cancer ; Finding Could Lead to Predictive Blood Test

"It gives us a new way of looking at genetic risk factors," said Dr. Teri Manolio of the National Human Genome Research Institute, the federal agency focused on such work.

It also...

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